Cell culture contaminations are a serious problem in biological research. Possible reasons are mostly mishandling of cells during routine culture and cryopreservation but also the lack of convenient tests for the quality control of cell cultures. The result is that 15-30 % of cell lines in current use are estimated to be contaminated or to not be what they are thought to be.
In principle, cell lines can be contaminated by a wide range of agents including i) bacteria, ii) viruses and iii) other cell lines. Frequent bacterial, viral and inter-species contaminations can be rapidly detected by Multiplexion´s Multiplex Cell Contamination Test. The patent for the underlying technology was granted in 2016 (WO 2009/109611). Contamination of one human cell line by another human cell line (intra-human contamination) and human cell line authentication is monitored by Multiplexion´s Multiplex Cell Line Authentication, which is based on Single Nucleotide Polymorphism (SNP) typing. For cell lines still not included in our SNP data base, classical Short Tandem Repeat (STR) profiling is offered.
Multiplexion offers the following quality control services:
Authentication of human cell lines and detection of intra-human cross-contaminations
Cell Contamination Testing |
Detection of 25 possible cell culture contaminations: SMRV, 12 different Mycoplasma species and contaminations with cells of 12 different animal species
Identification of 12 different Mycoplasma species, enabling tracing of Mycoplasma sources
You want to get to know Multiplexion?Every forth sample will be tested for free for first-time users. Valid only for the first order. No promo code is required. The special offer is only available for the following services:
Detection of 28 possible cell culture contaminations: SMRV, EBV, 13 different Mycoplasma species and contaminations with cells of 12 different animal species.
Authentication of human cell lines and detection of intra-human cross-contaminations by Multiplexion's multiplex SNP typing.
Authentication of human cell lines by classical STR profiling.
The special offer applies to purchases at list prices only and is not combinable with other discounts. Multiplexion may, at its sole discretion, terminate this offer at any time. Otherwise, the general terms and conditions of Multiplexion GmbH do apply.
The order of Multiplexion´s quality control services is very simple and no prior registration is needed for submitting your samples. Please follow one of the following links to access the our online order forms. Orders will become valid once we receive your samples.
Contamination testing |
- Multiplex Cell Contamination Test (SMRV, EBV, 13 Mycoplasma species and contaminations with cells of 12 different animal species)
- Mycoplasma Test
Cell Line authentication |